Ms Brigitte Hoffmann
CONTACT
E-mail: bhoff@unimelb.edu.au
Telephone: +61 3 9341 1576
QUALIFICATIONS
- BSc(Hons) (Monash)
SHORT HISTORY
- 1989 – 1992: Research Technologist at the Peter MacCallum Cancer Institute
- 1992 – present: Research Assistant at the University of Melbourne:
- Department of Microbiology
- Department of Medicine
- School of Dental Science
RESEARCH INTERESTS
- Molecular Biology
- Microbiology
CURRENT RESEARCH PROJECTS
- Identification of the prevalence of various oral pathogens in subgingival plaque samples using real-time PCR.
CURRENT PUBLICATIONS
- Butler CA, Dashper SG, Lissel, JP, Chiew, V, Hoffmann, B, Paolini, RA, O’Brien-Simpson, NM, Reynolds, EC. The Porphyromonas gingivalis Htr transport system plays a role in haem transport and is essential for virulence. In preparation.
- Dashper SG, Butler CA, Lissel JP, Paolini, RA, Hoffmann, B, Veith, PD, O’Brien-Simpson, NM, Snelgrove SL, Tsiros JT and Reynolds EC. (2005). A novel Porphyromonas gingivalis FeoB plays a role in manganese accumulation. Journal of Biological Chemistry, in press.
- Dashper SG, Paolini RA, O'Brien-Simpson NM, Hoffmann B, Cross, K, Malkoski, M, Veith, P and Reynolds EC. (2005). The interaction of the antibacterial peptide kappacin with divalent cations, Antimicrobial Agents and Chemotherapy, in press.
- Rajapakse PS, O'Brien-Simpson NM, Slakeski N, Hoffmann B, Reynolds. EC. Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model. Infect Immun. 2002 May;70(5):2480-6.
- O'Brien-Simpson NM, Paolini RA, Hoffmann B, Slakeski N, Dashper SG, Reynolds EC. Role of RgpA, RgpB, and Kgp proteinases in virulence of Porphyromonas gingivalis W50 in a murine lesion model. Infect Immun. 2001 Dec;69(12):7527-34.
- Jackson CA, Hoffmann B, Slakeski N, Cleal S, Hendtlass AJ, Reynolds EC. A consensus Porphyromonas gingivalis promoter sequence. FEMS Microbiol Lett. 2000 May1;186(1):133-8.