Dr Keith Cross
CONTACT
E-mail: keithjc@unimelb.edu.au
Telephone: +61 3 8344 2576
QUALIFICATIONS AND POSITION
- B.Sc(Hons), University of Western Australia, 1975
- Ph.D., University of Western Ontario, 1981
RESEARCH INTERESTS
- Nanotechnology: Structure-Function Studies of Casein Phosphopeptides*
- Structure-function studies and biomimetics of phosphorylated peptides and proteins.*
- Structure-function studies of salivary proteins*
- Bioinformatics of oral, craniofacial and dental disorders.*
CURRENT PUBLICATIONS
- CROSS, K. J., HUQ, N.L. and E. C. REYNOLDS (2003). Anticariogenic peptides. In: Nutraceutical Proteins and Peptides in Health and Disease.
- CROSS KJ, HUQ NL, BICKNELL W, REYNOLDS EC. Cation –dependent structural features of β-casein(1-25). Biochem. J. 356: 277-285 (2001).
- MALKOSKI M, DASHPER SG, O’BRIEN-SIMPSON NM, TALBO GH, MACRIS M, CROSS KJ, REYNOLDS EC. Kappacin, a novel antibacterial peptide from bovine milk. Antimicrob. Agents Chemother. 45: 2309-2315 (2001).
- CHEN YY, CROSS KJ, PAOLINI RA, FIELDING JA, SLAKESKI N, REYNOLDS EC. CPG70 is a novel basic metallocarboxypeptidase with C-terminal polycystic kidney disease domains from Porphyromonas gingivalis. J Biol Chem. 277:23433-23440 (2002).
- HUQ, N.L., CROSS, K.J., and REYNOLDS E.C. (2003) Nascent Helix in the Multiphosphorylated Peptide αs1-Casein(2-20). J. Peptide Sci. 9(6), 386-392
- HUQ, N.L., CROSS, K.J., and REYNOLDS E.C. (2004) Molecular modeling of the multiphosphorylated anticariogenic casein phosphopeptide αs1 Casein(59-79) based on NMR constraints. J Dairy Sci. 71, 1-5.
- CROSS, K.J., HUQ, N.L., STANTON, D., SUM, M., AND REYNOLDS, E.C. (2004) NMR Spectroscopy and mass spectroscopic studies of a novel calcium, phosphate and fluoride delivery vehicle-the multiphosphorylated peptide αs2-Casein(59-79) complexed with amorphous calcium fluoride phosphate. Biomaterials accepted Jan 2004.
- DASHPER, S. G.; CROSS, K. J.; SLAKESKI, N.; LISSEL, P.; AULAKH, P.; MOORE, C.; REYNOLDS, E. C. Hemoglobin hydrolysis and heme acquisition by Porphyromonas gingivalis. Oral Microbiology and Immunology. 19 (1) 50-56
CURRENT GRANTS
- NH&MRC "Anticariogenic casein phosphopeptide-amorphous calcium fluoride phosphate"
- Australian Dental Research Foundation 4 grants
MEMBERSHIPS
- ANZMAG
- IADR
- NY Academy of Science
TEACHING INTERESTS
- Postgraduate Common Core: Bioinformatics and Cheminformatics